The Normal Assay Control (NAC) plays a crucial role as a reliable standard in the assessment of various coagulation factors and proteins associated with hemostasis.
It serves as a standard control plasma for a comprehensive array of assays, including those for Factors II, V, VII, VIII, IX, X1, XI, XII, fibrinogen, von Willebrand Factor (VWF), and antigenic and functional Protein C and Protein S (both total and free). Additionally, the control is instrumental in chromogenic assays, covering Antithrombin III, Protein C, Factor VIII, and Plasminogen.
The values obtained for Factor II, VII, VIII, IX, and X, as well as chromogenic Factor VIII, Antithrombin III, and Protein C, are traceable to World Health Organisation standards. This adherence to international standards ensures the credibility and accuracy of the reported values. The NAC's primary function is to benchmark internal factors within each laboratory's testing system.
The NAC is vital in factor VIII assays, also known as FVIII assays, which evaluate the concentration of factor VIII in the plasma. The control aids in chromogenic assays for factor VIII, ensuring precise measurement and consistency in results. It is also a key component in testing for von Willebrand Factor (VWF) protein, influencing assays related to VWF and those for assessing other coagulation factors.
The NAC's role in FVIII testing, chromogenic factor VIII assays, and Von Willebrand Factor protein assays is integral in maintaining the quality and accuracy of laboratory analyses. It use as a standard ensures that laboratories can confidently evaluate and monitor the performance of their testing systems, contributing to the overall reliability of coagulation testing in clinical settings.
NAC is supplied as the following:
The Normal Assay Control (NAC) plays a crucial role as a reliable standard in the assessment of various coagulation factors and proteins associated with hemostasis.
It serves as a standard control plasma for a comprehensive array of assays, including those for Factors II, V, VII, VIII, IX, X1, XI, XII, fibrinogen, von Willebrand Factor (VWF), and antigenic and functional Protein C and Protein S (both total and free). Additionally, the control is instrumental in chromogenic assays, covering Antithrombin III, Protein C, Factor VIII, and Plasminogen.
The values obtained for Factor II, VII, VIII, IX, and X, as well as chromogenic Factor VIII, Antithrombin III, and Protein C, are traceable to World Health Organisation standards. This adherence to international standards ensures the credibility and accuracy of the reported values. The NAC's primary function is to benchmark internal factors within each laboratory's testing system.
The NAC is vital in factor VIII assays, also known as FVIII assays, which evaluate the concentration of factor VIII in the plasma. The control aids in chromogenic assays for factor VIII, ensuring precise measurement and consistency in results. It is also a key component in testing for von Willebrand Factor (VWF) protein, influencing assays related to VWF and those for assessing other coagulation factors.
The NAC's role in FVIII testing, chromogenic factor VIII assays, and Von Willebrand Factor protein assays is integral in maintaining the quality and accuracy of laboratory analyses. It use as a standard ensures that laboratories can confidently evaluate and monitor the performance of their testing systems, contributing to the overall reliability of coagulation testing in clinical settings.
NAC is supplied as the following:
