Hart Biologicals Thrombin Receptor Activator Peptide -6 (TRAP-6) Reagent is used to diagnose platelet dysfunction, or normal platelet activity in human platelet rich plasma or whole blood.
TRAP-6 is a synthetic hexapeptide that activates the thrombin receptor independent of receptor cleavage. It corresponds to amino acids 42 to 47 of the thrombin receptor and mimics the effects of thrombin. Thrombin is a very potent platelet activator. Its action is not blocked by anti-platelet drugs such as Aspirin or Clopidogrel. TRAP-6 can be used as an alternative to Thrombin as a platelet activator as it is easily standardized and more stable than thrombin. TRAP-6 can be used to detect the action of GpIIb/IIIa antagonists such as Reopro, Aggrastat or Integrillin.
The reagent is supplied for simple reconstitution with 1.0ml distilled water.
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