Arachidonic Acid 5mg/ml - 1 x 1.0ml
Assay Platelet Aggregation Product No. HB-5505-FG
Arachidonic Acid 5mg/ml - 1 x 1.0ml
Product Description


Hart Biologicals Arachidonic Acid reagent is used to diagnose platelet dysfunction, or normal platelet activity in human platelet rich plasma or whole blood.

The platelet aggregation test measures the rate and degree to which dispersed platelets in a sample of platelet rich plasma (PRP) or anti-coagulated whole blood forms clumps (aggregates) after the addition of a substance that normally stimulates platelet aggregation (agonist).

Arachidonic acid is a fatty acid present in the granules and membranes of human platelets. It is liberated from phospholipids and, in the presence of the enzyme cyclo-oxygenase 1 (COX-1), incorporates oxygen to form the endoperoxide prostaglandin G2 (PGG2). PGG2 is then quickly transformed to prostaglandin H2 (PGH2) which in turn is converted to thromboxane A2 a potent inducer of platelet aggregation. In vitro addition of Arachidonic acid to normal platelet rich plasma results in a burst of oxygen consumption, thromboxane formation and platelet aggregation

Hart Biologicals Arachidonic Acid Reagent is supplied as the following for reconstitution with 1.0ml distilled water:

·         1 x 1.0ml 5mg/ml Arachidonic Acid

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