Hart Biologicals Factor XII deficient plasmas are human source plasma immunodepleted of that particular coagulation factor while having the other clotting factors within normal limits. Factor XII Deficient Plasma along with the other Intrinsic Pathway Factor Deficient Plasmas are recommended for use as a deficient substrate in clot based factor assays using the Activated Partial Thrombolplastin Time (aPTT).
Factor XII is also known as Hageman factor. The activated form of Factor XII activates factor XI and Prekallikrein. Factor XII itself can be converted to its active form Factor XIIa by negatively charged surfaces.
Factor XII Deficient Plasma is suppliied in the following kit sizes: