The Hart Biologicals Ristocetin co-factor assay kit tests von Willebrand factor activity by gauging patient plasma's capacity to agglutinate formalin-fixed platelets in the presence of ristocetin.
Hart Biologicals Ristocetin co-factor assay kit is supplied as:
· 4 x 6ml lyophilised formalin-fixed human platelets
· 2 x 1ml 10mg/ml Ristocetin lyophilised
· 2 x 1.0ml Reference standard derived from normal human plasma - lyophilised
· 2 x 0.5ml Abnormal control derived from human plasma
· 2 x 25ml Tris-buffered saline with preservatives and stabilisers
Clotting factors, proteins that assist in the clotting process, help to stop excessive bleeding. The ristocetin cofactor test checks the activity of von Willebrand factor, used to evaluate how well the protein is functioning.
Clotting factors act in a specific sequence to form a clot. If there is an insufficient amount of them or they don't work correctly, then the blood may take longer to clot.
Von Willebrand factor (VWF) is involved in clotting and can lead to von Willebrand disease if the gene is abnormal. To diagnose such disorders, doctors must measure the levels and activity of VWF. Various tests are used to assess activity due to VWF's multiple functions that aid in preventing bleeding.
Assays measure VWF activity by observing how much VWF binds to platelets/particles. Ristocetin aids in detection. The most frequent VWF:RCo assays include platelet agglutination, latex agglutination, and chemiluminescent assay (CLIA).
Laboratory Testing for von Willebrand Factor Ristocetin Cofactor (VWF:RCo) - Soma Mohammed & Emmanuel J. Favaloro
Note: To download a copy of this Product's Instructions For Use in English, create an account by clicking 'Register'. Other European languages, including French, German, Spanish and Italian are available upon request.
The Hart Biologicals Ristocetin co-factor assay kit tests von Willebrand factor activity by gauging patient plasma's capacity to agglutinate formalin-fixed platelets in the presence of ristocetin.
Hart Biologicals Ristocetin co-factor assay kit is supplied as:
· 4 x 6ml lyophilised formalin-fixed human platelets
· 2 x 1ml 10mg/ml Ristocetin lyophilised
· 2 x 1.0ml Reference standard derived from normal human plasma - lyophilised
· 2 x 0.5ml Abnormal control derived from human plasma
· 2 x 25ml Tris-buffered saline with preservatives and stabilisers
Clotting factors, proteins that assist in the clotting process, help to stop excessive bleeding. The ristocetin cofactor test checks the activity of von Willebrand factor, used to evaluate how well the protein is functioning.
Clotting factors act in a specific sequence to form a clot. If there is an insufficient amount of them or they don't work correctly, then the blood may take longer to clot.
Von Willebrand factor (VWF) is involved in clotting and can lead to von Willebrand disease if the gene is abnormal. To diagnose such disorders, doctors must measure the levels and activity of VWF. Various tests are used to assess activity due to VWF's multiple functions that aid in preventing bleeding.
Assays measure VWF activity by observing how much VWF binds to platelets/particles. Ristocetin aids in detection. The most frequent VWF:RCo assays include platelet agglutination, latex agglutination, and chemiluminescent assay (CLIA).
Laboratory Testing for von Willebrand Factor Ristocetin Cofactor (VWF:RCo) - Soma Mohammed & Emmanuel J. Favaloro
Note: To download a copy of this Product's Instructions For Use in English, create an account by clicking 'Register'. Other European languages, including French, German, Spanish and Italian are available upon request.
